Cosmetic injectables are FDA-approved treatments designed to temporarily improve the appearance of moderate to severe frown lines, crow’s feet, and forehead lines in adults. These treatments work by relaxing targeted facial muscles that contribute to expression lines. Treatment requires minimal downtime, and most patients can return to their normal daily routine immediately after leaving the office. Some individuals begin to notice visible improvement within 24 to 48 hours, with full results typically developing within two weeks. Cosmetic injectables deliver predictable, natural-looking results — helping you look refreshed and like yourself, with softer, less noticeable facial lines.
Cosmetic injectables target one of the underlying causes of frown lines, crow’s feet, and forehead lines — repeated muscle contractions from facial expressions such as frowning, squinting, smiling, and raising the eyebrows over time. During treatment, small amounts of the injectable are precisely administered into specific facial muscles to temporarily reduce muscle activity. As these muscles relax, the overlying skin appears smoother, and expression lines become softer and less noticeable. Patients typically notice visible improvement in the treated areas within several days, with results continuing to develop over the following one to two weeks.
Cosmetic injectables are technique-sensitive treatments. When performed by a licensed and experienced medical professional with advanced knowledge of facial anatomy, results are designed to be subtle and natural-looking. The goal is to soften lines while preserving normal facial expression, so you still look like yourself — just more refreshed. When administered properly, the results should enhance your appearance without looking overdone or obvious. If you have additional FAQ entries, send them over and I’ll keep everything consistent in tone and compliance.
Not at all. Cosmetic injectables are increasingly popular among both men and women who want to maintain a refreshed, well-rested appearance.
In recent years, the number of men choosing wrinkle-relaxing treatments has grown significantly. Many men seek treatment for common concerns such as crow’s feet, forehead lines, and frown lines. These treatments can provide subtle, natural-looking results that help soften expression lines while preserving a masculine appearance.
Cosmetic injectables are customized for each patient, ensuring results that align with individual facial structure and aesthetic goals.
Age alone does not determine when cosmetic injectables may be appropriate — it depends more on the presence and severity of expression lines. Many adults in their 30s choose wrinkle-relaxing treatments as part of a proactive approach to maintaining a smooth, refreshed appearance.
Everyone’s skin ages differently. The development of fine lines and wrinkles can be influenced by several factors, including natural cellular changes over time, reduced collagen production, genetics, and environmental exposure such as sun damage.
A consultation with a qualified medical provider can help determine the right timing and treatment approach based on your individual concerns and aesthetic goals.
Your provider will begin by discussing your treatment goals and performing a detailed facial assessment to determine the most appropriate areas for treatment. If you are a suitable candidate, the procedure can often be performed during the same visit.
The injection process typically takes about 15–30 minutes, depending on the number of areas treated. Most patients describe the sensation as a quick pinch or mild pressure. To enhance comfort, your provider may use ice to numb the treatment area or apply a topical numbing cream prior to the injections if needed.
Cosmetic injectable treatments require minimal downtime, allowing you to return to your normal daily activities immediately after your appointment.
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Many patients begin to notice visible improvement within 24 to 48 hours after treatment, with full results typically developing within 10 to 14 days. Individual response times may vary.
Results from wrinkle-relaxing injectables generally last about three to four months, depending on the treatment area, metabolism, and individual factors. To maintain optimal results, your provider will recommend a personalized treatment schedule based on your response and aesthetic goals.
Treatment requires minimal downtime. So you can return to your daily routine immediately after you leave your specialist’s office.
Cosmetic injectable treatment is customized to your individual goals and facial anatomy. During your consultation, your provider will evaluate the areas you wish to address — such as frown lines, crow’s feet, or forehead lines — and determine the appropriate treatment plan.
The number of injections varies depending on the treatment area and the severity of the lines. For example, treating crow’s feet typically involves several small injections placed in the muscles at the outer corners of each eye. Frown lines between the brows and forehead lines may also require multiple precise injections to ensure balanced, natural-looking results.
Three percent of patients experienced eyelid drooping in the frown lines studies, one percent of patients experienced eyelid swelling in the crow’s feet studies, and one percent of patients experienced brow drooping in the forehead lines studies. Other possible side effects include: dry mouth; discomfort or pain at the injection site; tiredness; headache; neck pain; eye problems: double vision, blurred vision, decreased eyesight and dry eyes; and allergic reactions. These are not all of the possible serious side effects of botox® cosmetic. Please see the important safety information including boxed warning and medication guide and talk to your specialist.
There are several FDA-approved wrinkle-relaxing injectable products available, and each has its own formulation, dosing guidelines, and clinical profile. These products are not interchangeable, and treatment selection should always be based on a provider’s clinical judgment and your individual needs.
Patients should be cautious of heavily discounted or unusually low-cost offers, as proper storage, handling, and dosing are essential for both safety and effectiveness. Injectable treatments should only be administered by a qualified medical professional using FDA-approved products obtained through legitimate medical suppliers.
During your consultation, your provider will discuss the most appropriate treatment option for you and ensure that it is administered safely and according to established medical standards.
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JUVÉDERM® is the #1 selling collection of hyaluronic acid fillers in the U.S. Each product in the JUVÉDERM® Collection of Fillers adds volume to a different area of the face—without surgery. All JUVÉDERM® fillers are smooth, crystal-clear gels that are administered by injection in your aesthetic healthcare provider’s office.
Different formulations are approved to either volumize cheeks, smooth facial wrinkles and folds, smooth lines around the mouth, or plump the lips. The results are subtle and long-lasting.
JUVÉDERM® VOLLURE® XC softens moderate to severe facial wrinkles and folds by adding volume around the nose and mouth in adults over the age of 21.
JUVÉDERM® VOLUMA® XC injectable gel is for deep injection in the cheek area to correct age-related volume loss and for augmentation of the chin region to improve the chin profile in adults over 21.
JUVÉDERM® VOLBELLA® XC adds subtle volume to lips and softens the appearance of perioral lines.
JUVÉDERM® ULTRA PLUS XC smooths moderate to severe facial wrinkles and folds around your around your nose and mouth.
JUVÉDERM® ULTRA XC adds fullness and plumps lips as well as smooths and corrects moderate to severe wrinkles and folds in adults.
Products in the JUVÉDERM® Collection are FDA approved and have been widely studied. Numerous clinical studies have been completed globally evaluating the safety and effectiveness of Vycross® technology fillers. Please see below for more Important Safety Information.
The JUVÉDERM® Collection of Fillers is made from hyaluronic acid (HA). HA is a natural substance in the skin that delivers nutrients, helps the skin retain moisture and softness, and adds volume. Each product in the JUVÉDERM® Collection of Fillers is made from a modified form of HA.
Your aesthetic healthcare provider will take your medical history and provide a facial analysis. Be prepared to discuss your aesthetic areas of concern. This is not a surgical treatment. Actual treatment with JUVÉDERM® injectable gels can take 15 minutes to 60 minutes, depending on which area of your face is being treated.
JUVÉDERM® injectable gels labeled with “XC” contain pain-reducing lidocaine to help manage pain or discomfort during the injection. You may also ask your aesthetic healthcare provider about a topical numbing cream or ice to help further minimize discomfort.
You will see results immediately/instantly.
Results may last one year to two years, with optimal treatment and depending on the formula used and the area treated. Please read each product description to see how long results last with each formula and treatment area, based on what was observed in clinical studies.
Do not receive JUVÉDERM® injectable gel fillers if you have a history of severe allergic reactions (anaphylaxis), or if you are allergic to lidocaine or the proteins (Gram-positive bacterial proteins) used to make hyaluronic acid (HA) in JUVÉDERM® injectable gel fillers.
Treatment with JUVÉDERM® fillers is not permanent. Depending on the JUVÉDERM® filler used and the treatment area, results may last one year to two years with optimal treatment.
The most common side effects are redness, swelling, pain, and tenderness. Minimize exercise, sun or heat exposure, and alcoholic beverages within the first 24 hours following treatment to avoid worsening these side effects. Talk to your licensed specialist about post-care instructions following treatment and please see below for more Important Safety Information.
The Restylane family of products is a brand of hyaluronic acid dermal fillers, which includes Restylane Silk, Restylane Lyft, Restylane, Restylane Refyne and Restylane Defyne. Each is a clear gel formulation of hyaluronic acid specifically formulated to act like your body’s own naturally produced hyaluronic acid. Each Restylane product is designed for a specific purpose.
Restylane Silk is the first FDA-approved product specifically designed for subtle lip augmentation and the smoothing of wrinkles around the mouth. It is composed of a gel that is smaller and smoother than other Restylane products, resulting in a softer, more precise result — ideal for restoring and enhancing the lips. Additionally, Silk is administered via ultrafine needle, which is designed for improved accuracy and precision.
Restylane Lyft is approved by the FDA to correct volume deficit in the back of the hands, for cheek augmentation and the correction of age-related midface contour deficiencies, as well as the treatment of moderate to severe facial folds, such as the nasolabial folds (smile lines). Lyft is the first and only hyaluronic filler approved by the FDA to treat face and hands. Lyft contains 0.3% lidocaine, which is added to reduce the discomfort during treatment.
Restylane is used to add volume and fullness to the skin to correct moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds). Restylane is also indicated for lip augmentation.
Restylane Refyne integrates with your skin to help smooth out the lines that run alongside the corners of your mouth (nasolabial folds and marionette lines) and the flexibility you need for natural-looking movement and expressions.
Restylane Defyne is designed to act like your body’s own hyaluronic acid to help smooth out deeper lines around your mouth (nasolabial folds and marionette lines) while letting you look more natural through a range of facial expressions.
Restylane products are approved only for patients over the age of 21.
Dermal fillers are facial injection treatments used to help diminish wrinkles while restoring volume and fullness in the face and hands. There are several types of dermal fillers, one being hyaluronic acid. All Restylane products are transparent hyaluronic acids, which are sugars naturally found in the skin that help provide hydration, fullness and elasticity.
Wrinkles are part of life — our skin changes as we age. It becomes thinner, loses fat, and no longer looks as plump and smooth as it once did. Facial aging actually begins in your 20s, when skin firmness begins to decrease as a result of both internal (genetics and natural aging) and external (sun exposure, smoking, stress, etc) factors.
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Hyaluronic acid is a naturally occurring substance in your skin that helps provide fullness and elasticity, with the help of collagen and elastin.
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Hyaluronic acid, collagen, and elastin diminish as we age, causing skin to lose volume, while increasing the chances for wrinkles and folds to appear.
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What causes the appearance of aging in hands?
As part of the natural aging process, volume in the hands can deteriorate over time, making them appear aged. Veins, tendons and bones may become more visible.
The “cupid’s bow” is the double curve of the upper lip, resembling the bow of Cupid, Roman god of love. The upper lip is believed to be most attractive when it is well-defined and when the two sides look the same. Everyone’s facial structure is different, and so is everyone’s ideal lip shape and size. Restylane Silk is designed to provide precise lip shaping and line control, resulting in silkier, smoother lips and natural-looking results.
With full treatment, you can see lasting results for up to 18 months in nasolabial folds with Restylane; up to 12 months in the cheeks, up to 6 months in the back of the hands, and up to 6 months in facial wrinkles and folds, such as nasolabial folds, with Restylane Lyft; 6 months for lips and perioral rhytids with Restylane Silk; and up to 12 months in the facial wrinkles and folds (such as nasolabial folds and marionette lines) with Restylane Refyne and Restylane Defyne.
Restylane Silk: In clinical studies, the results of Restylane Silk lasted approximately 6 months following treatment. In a U.S. clinical trial involving 221 mostly female subjects, 98% of subjects reported a visible improvement in lip fullness in upper and lower lip (combined) 14 days after injection, and 77% still had lip improvement at 6 months following injection.
Restylane Lyft: In a clinical trial involving 150 subjects, blinded evaluators observed that 90% of subjects treated with Restylane Lyft showed an improvement in fullness in the right and left midface areas (combined) at 2 months, and 54% of subjects showed an improvement at 12 months. Additionally, 95% of subjects reported that they were satisfied with the appearance of their midface at 2 months, and 73% of subjects were satisfied at 12 months. In a clinical trial involving 89 treated subjects, blinded evaluators observed that 86% of subjects* treated with Restylane Lyft showed an improvement in volume of the back of the hands at 3 months, and 76% of subjects* showed an improvement at 6 months.
Restylane: In a clinical study treating the lines from the nose to the corners of the mouth (laugh lines), blinded evaluators reported that 95% of subjects improved for up to 18 months when they received an initial Restylane treatment, plus a follow-up treatment approximately 4.5 or 9 months later. Using this Restylane regimen of treatments, blinded evaluators reported similar subject improvement, on average, at 18 months compared to their Week 2 Wrinkle Severity Rating Scale (WSRS) score.
Restylane Refyne & Restylane Defyne: In a clinical study of subjects treated for laugh lines with Restylane Refyne and Restylane Defyne, investigators reported improvement in the appearance of wrinkles for up to 12 months in the majority of patients. Using the Wrinkle Severity Rating Scale (WSRS), a validated 5-point measure of the size and depth of the wrinkles, with grade 1 defined as absence of wrinkles and grade 5 as extremely deep and long wrinkles, investigators reported that 79% of Restylane Refyne subjects and 77% of Restylane Defyne subjects had at least a 1-grade improvement on the WSRS after 6 weeks. Subjects also performed self-assessments (SSA) of wrinkle severity, with most reporting at least a 1-grade improvement in SSA scores with Restylane Refyne and with Restylane Defyne after 6 weeks.
*The duration of effectiveness of Restylane for the correction of nasolabial folds (NLFs) was evaluated in a randomized, evaluator-blinded multicenter study. Restylane was shown to have an overall duration of effectiveness of 18 months from baseline following retreatment at 4.5 or 9 months.
Depending on your volume needs, most Restylane treatment appointments last less than an hour and begin to work almost immediately by adding volume to smooth away wrinkles. A clear gel formulation of hyaluronic acid, Restylane products act like your body’s own hyaluronic acid (and eventually break down naturally). Each Restylane product is designed for a specific purpose.
After your treatment, you may experience side effects, such as swelling, redness, pain, bruising, headache, tenderness, lump formation, itching at the injection site and impaired hand function. These are typically mild in severity and normally last less than 7 days in nasolabial folds and less than 14-18 days in lips. Patients should be limited to 6.0 mL per treatment of moderate to severe facial wrinkles and folds. For treatment of volume deficit in the hands, patients should be limited to 3.0 mL per hand per treatment. Swelling may be more likely in patients under 36 years, and bruising may be more likely in patients over 35 years.
Initial Restylane treatments are usually complete in one or two sessions, as needed. Depending on your individual body chemistry, you will work with your specialist to determine a maintenance schedule. Talk to your physician or healthcare professional about your individual needs.
The Restylane family of products should not be used by people who:
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Are pregnant, breastfeeding, or under 22 years of age
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Have recently used drugs that thin the blood or prevent clotting
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Have had previous bad allergies, particularly to microorganisms known as gram-positive bacteria
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Have serious allergies to drugs that have previously required in-hospital treatment
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Have bleeding disorders
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Have a known allergy to lidocaine, if using Restylane Silk, Restylane lyft, Restylane, Restylane Refyne or Restylane Defyne
